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4,6,7 Opioid replacement therapy not only mitigates these changes in neurotransmitters but is also associated with apoptosis, white and grey matter injury, altered redox homeostasis, and changes in oligodendroglial maturation and myelination, which may be particularly damaging in the developing brain

da Silva-Arajo ER, Manhes-de-Castro R, Pontes PB et al (2023) Effects of riboflavin in the treatment of brain damage caused by oxygen deprivation: an integrative systematic review

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