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Animal Model:C57BL/6J mice [4] Dosage:100 mg/kg Administration:Oral gavage

This has been shown to depend on the activation of a key cellular energy sensor, AMP-activated protein kinase (AMPK) 129132

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Estimates of increased relative risk range from 10% to 50% or more, based on the drug and dose studied

Within 48 hours after injection of 100 or 1,000 mcg of vitamin B 12 , 50 to 98% of the injected dose may appear in the urine

Focus on a balanced diet with plenty of fruits, vegetables, lean proteins, and healthy fats