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More specifically, data available so far strongly suggest that H 2 S may become the next potent preventive and therapeutic agent for preventing and ameliorating the symptoms of aging and age-associated diseases, and this should be addressed in future studies

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59,60 Folate-mediated one-carbon metabolism Folate-mediated one-carbon metabolism has been long recognized and attributed to its function of producing one-carbon units for nucleic acid and methionine synthesis, another crucial function of this pathway is generating reducing power NADPH

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