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Description

A has also been demonstrated to activate microglia and result in inflammatory damages [11]

gingivalis may act as a mimic antigen to induce autoimmunity

Secondly, NRF2 can reduce the senescence-associated secretory phenotype (SASP) by modulating oxidative stress, endoplasmic reticulum stress, inflammation, immune response, and cell cycle arrest [46]

The mutant huntingtin protein (mHTT) exhibits a higher propensity for aggregation, forming toxic oligomers and insoluble protein aggregates that accumulate in the nucleus and cytoplasm [114]

And that it did

Notably, glutamate and cysteine are linked by an unconventional -linkage peptide bond, which can be hydrolyzed only by -glutamyl transpeptidase (GGT) (2, 55)