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Salidroside potentially lowers blood glucose in diabetic mice by altering the gut microbiota and modulating iron metabolism, offering protection against diabetic cardiomyopathy [189]

Polyphenols and Neuroprotection Polyphenols play a significant role in neuroprotection by targeting key mechanisms implicated in neurodegenerative diseases like AD, Parkinson's disease (PD), and other cognitive disorders

This leads to membrane lipid peroxidation and ultimately ferroptosis [25]

But general guidelines do exist

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Citrate lyase is a key enzyme of citrate fermentation, the prosthetic group of citrate lyase is catalyzed by CitG and CitX in Escherichia coli