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Furthermore, in the event of overdose, hypotension or hypertension may occur, as well as a negative impact on mental health with mood swings, agitation, even depression and panic attacks.

et al., 2020)

Another study has shown that hepatocyte-conditional NIK deficiency alleviates nonalcoholic steatohepatitis (NASH), which involves a mechanism that is independent of NF-B but involves attenuation of JAK2-STAT5 signaling axis [28]