This multi-pathway approach offers both immediate enhancement of cognitive processes and long-term protection against neuronal damage, representing a holistic strategy for brain health and performance
Just remember, the effects are temporary
However, redox homeostasis is conditioned by the magnitude and duration of exposure to free radicals, since constant exposure can have a serious impact on intracellular signals or genetic expression, resulting in irreversible pathological consequences (Rhee et al., 2003), since most reactions of the body are dependent on the redox state (Tan et al., 2018)
This could be related to the established role of GSK-3 in innate immunity as it is necessary for I k B phosphorylation leading to downstream NF-B induction that is key for pro-inflammatory cytokine signaling, and also the induction of a type 1 IFN antiviral responses, forming immunocomplexes with factors such as with TANK-binding kinase 1 (TBK1), that is responsible for IFN regulatory factor 3 phosphorylation and subsequent signaling and other factors (Marineau et al., 2020
This provides backup if questions or concerns arise
Its antioxidant and anti-inflammatory abilities fight oxidative damage and chronic inflammation, while its effects on cell proliferation and apoptosis fight cancer, notably digestive tract malignancies
