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S.ProticO.GiannubiloS

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Extracellular vesicles as an emerging treatment option for intervertebral disc degeneration: therapeutic potential, translational pathways, and regulatory considerations

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10.3390/pharmaceutics13040508 161 SilvaA

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Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ

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High doses of Put (2.5 mM) can induce mild metabolic stress, e.g., by increasing the production of HO as a byproduct of amine oxidation and shifting metabolic pathways towards proline synthesis 66

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