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A major advancement in the development of apoE-based gene therapies was recently reported with the AAV-mediated expression of an apoE variant combining the apoE2 and Christchurch variant in amyloid and tau-based AD mouse models

Estimating intestinal absorption of inorganic and organic selenium compounds by in vitro flux and biotransformation studies in Caco-2 cells and ICP-MS detection

Yale Digestive DiseasesTemple Medical Center40 Temple Street, Ste Suite 1ANew Haven, CT 06510 Yale New Haven Hospital20 York StreetNew Haven, CT 06510 Yale Digestive DiseasesTemple Medical Center40 Temple Street, Ste Suite 1ANew Haven, CT 06510 Yale New Haven Hospital20 York StreetNew Haven, CT 06510

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Glutathione is a small peptide composed of three amino acids cysteine, glutamic acid, and glycine and is produced in virtually every cell of the body, with particularly high concentrations found in the liver

doi: 10.1002/mrm.20978, 41 GriswoldM