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This metabolic milieu generates reactive oxygen species (ROS) that can damage photoreceptor cells, retinal pigment epithelium, and choroidal vasculature

Baseline bloodwork should include a comprehensive metabolic panel, fasting insulin, fasting glucose, HbA1c, lipid panel, liver enzymes (AST and ALT), IGF-1 levels, thyroid panel, and for men, testosterone levels

Acknowledgments The authors would like to thank the Long Island University Dassault Systmes Centre of Excellence for their financial and resource support

10.1007/s13311-017-0582-3 7 CaoXY.NiJH.WangX.FengGZ.LiHD.BaoWL.et al (2021)

In childhood the disease normally takes a much more aggressive course than when it appears in teenagers and young adults

These rats either received a placebo or 100ug/kg hexarelin twice a day for 30 days