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Nicotinamide adenine dinucleotide (NADH/NAD + ) and its phosphorylated forms (NADPH/NADP + ) are also important cofactors and core metabolites in the body and are closely related to the synthesis of amino acids, often used as key indicators to evaluate cellular metabolism (Christensen et al., 2017

Hauser RA, Schapira AH, Rascol O, Barone P, Mizuno Y, Salin L, Haaksma M, Juhel N, Poewe W

Throughout the aging process melatonin levels tend to reduce and as a manifestation of this, many symptoms in organisms homeostasis, such as deterioration in adjustment of cellular clocks, are commonly seen

doi: 10.1111/jog.14858 61 AbdelazeemBAbbasKSShehataJBaralNBanourSHassanM

Biochem J 292: 477483, 1993 Shaw JP, Chou IN: Elevation of intracellular glutathione content associated with mitogenic stimulation of quiescent fibroblasts

Sermorelin has the longest history of clinical use among this group