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Description

Enhancing CD8(+) T-Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy

To further confirm the binding between self-assembled Gi-F-CAA and GPX4, EJ cell was treated with NBD labeled Gi-F-CAA followed by anti-GPX4 monoclonal antibody treatment

By systematic screening and optimization, we demonstrated that coating of ~5 molar% DSPECD47p gave the most consistent physicochemical properties as AZEpaclitaxome-2 (Supplementary Table 9 and Fig