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Individuals with a history of gastrointestinal surgery or disorders such as Crohns disease, celiac disease, or pernicious anemia may have difficulty absorbing adequate amounts of B12 and folate from their diet, and may require supplementation

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doi: 10.1007/s00216-011-4962-y, PMID: [DOI] [PubMed] [Google Scholar] 211.Malvindi MA, di Corato R, Curcio A, Melisi D, Rimoli MG, Tortiglione C, et al

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For example, carcinogens ingested during cigarette smoking are associated with specific mutational signatures across almost all human cancer types, including bladder cancer [110]

Your gut bacteria need to be fed (prebiotics), replenished (probiotics), and supported with the beneficial compounds they produce (postbiotics)