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Depression Depression is a prevalent mental health disorder that significantly impairs psychosocial functioning and diminishes overall quality of life (Oikonomou et al

Culture of isolated adult neurons was as previously described [19]

The analysis of neuron density further supports these findings, with the model group showing a marked reduction in neuron density (Figure 8C), reflecting the adverse effects of sleep deprivation on neuronal health

Timelines vary, but improvement may be seen within a few months, depending on individual response

Koyyada A, Orsu P

We only examined the total mTOR expression to explore the correlation between this protein and the pain process