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Potential relationship to administration of study drug as assessed by the investigator was: 25 possibly and 39 unlikely for the ARA 290 group, and 40 possibly and 26 unlikely for the placebo group

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409,410 A phase I clinical trial involving 80 patients investigated the pharmacokinetics and pharmacodynamics of ATN-224

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24 h) inhibits the activation of the NLRP3 inflammasome and protects human podocytes (HPC) from TNF--induced injury [1]

Conversely, no significant increase was observed in the expression of other glucose transporters (Supplementary Fig