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These neurotoxins, upon accumulation, can alter the functioning of the nervous system by altering the electrical and chemical transmission

In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status

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After decapitation, a laparotomy was performed and the left kidney was removed and cleaned with ice-cold normal saline

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In order to meet high metabolic demands, the brain produces large amounts of energy, mainly from glucose oxidation (Raichle & Gusnard, 2002)