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As a widespread model animal in research areas such as development, molecular genetics, toxicology and biomedicine 26,27 , zebrafish ( Danio rerio ) has been used in mechanistic studies of fish nutrition 28,29

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On the other hand, data from sub-chronic and chronic antidepressant treatment are conflicted , probably due to variable treatment duration and differences in the time and method of sampling

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In the outcome of changes in the ALT levels, moderate credibility of ICEMAN result shows that L-carnitine supplementation has no difference in changes in younger ones (MD: 0.4, 95%CI: 1.32 to 2.12) but has significant changes (reduced) in adults (MD: 31.7, 95%CI: 47.61 to 15.79)