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Do peptides cause muscle loss along with fat loss

The SURMOUNT-3 trial showed that combining tirzepatide with intensive lifestyle intervention produced 26.6% weight loss versus approximately 21% with medication alone over similar timeframes

Endocrinology 2001

Sampson CM, Dimet AL, Neelakantan H, et al

Research suggests that it works by stimulating lipolysis (fat breakdown) and inhibiting lipogenesis (fat accumulation), particularly in stubborn fat deposits such as the abdomen and thighs

If you plan to resume, restart at the full dose rather than titrating back up, since the break period allows receptor resensitization