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Y.XiY.WangL

Determining the correct B12 dosage can be tricky, as the appropriate amount depends on factors such as age, the severity of deficiency, and any coexisting conditions

doi: 10.1038/nature08938 38 EndemannG.StantonL.MaddenK

Magnesium helps here, too

This results in closure of the ATP-sensitive K + channels, decreasing the hyperpolarising outward K + flux, depolarising the plasma membrane and opening voltage-gated Ca 2+ channels to increase the influx of extracellular Ca 2+ , which is a primary driver of the mechanism of glucose-stimulated insulin secretion (GSIS)