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Usually found in animal produce (dairy, eggs, meat), vegetarians and vegans are particularly prone to B12 deficiency but it can affect anyone, causing tiredness, fatigue and even cognitive changes in some cases

It is not known if supplementation with choline will lower the occurrence of NTDs

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The authors reported that intra-articular AOD-9604 injection in the rabbit osteoarthritis model produced macroscopic, histologic, and biomechanical evidence of cartilage preservation relative to untreated controls, with the combination of AOD-9604 plus hyaluronic acid yielding the most consistent chondroprotective effect [4]

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Additionally, DSIP may play a role in stress reduction, mood regulation, and pain management