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Deferoxamine reduces endothelial ferroptosis and protects cerebrovascular function after experimental traumatic brain injury

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3.6.3.2 Microbial metabolites A substantial body of research highlights the role of gut microbiota and their metabolites, particularly SCFAs, in regulating metabolic, endocrine, and immune functions, with emerging evidence pointing to their involvement in neuro-immunoendocrine pathways through the MGBA (Silva et al., 2020)

After extensive experiments, MC3181 was deemed the more promising compound of the two, due to it having a 50-fold rise in aqueous solubility and higher selectivity toward GST

doi: 10.1530/EC-20-0152 102 Gallego-EscuredoJMGmez-AmbrosiJCatalanVDomingoPGiraltMFrhbeckGet al

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