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The key histological abnormalities of AD include necrosis and apoptosis of VSMCs, fracture of elastic fibers, and degradation of extracellular matrix (ECM) (73).The thrombi formed within the false lumen indicates the presence of continued inflammation under the condition of atherosclerosis and chronic inflammation, and the higher risk of rupture in patients with inflammatory diseases demonstrates the importance of inflammation in AD (74)

Whole blood samples were assayed for standard cell blood counts with percentage differentials [i.e., hemoglobin, hematocrit, platelet, red blood cell counts, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell distribution width (RDW), white blood cell counts (neutrophils, lymphocytes, monocytes, eosinophils, basophils)

Other exclusions were added as necessary

ACT-based immunotherapies can elicit significant tumor regression in animal models and also up to 70% of metastatic melanoma patients

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Kaneko et al