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The second mechanism involves inhibition of clonogenic cell growth, potentially via downregulation of RRM2 and DNA damage, leading to accumulation of DNA breaks and cell cycle blockade

Post-Surgery Patients : People who have undergone intestinal surgery, including weight loss surgery (like gastric bypass), may have reduced capacity to absorb B12

Vitamin B3: Niacin (vitamin B3) is a strong vasodilator, meaning it dilates blood vessels to allow more oxygen and nutrients to enter the body, especially the brain

Rather than being associated with an IF-mediated inability to absorb vitamin B 12 , in 3040% of cases SCCD occurs as a consequence of FBCM

B12 is also added to certain foods, like cereals

"Why is B12 Difficult to Absorb and Do Oral B12 Sprays Work?"