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Summary: Calorie restriction is often reported to lower IGF-1 levels, but studies have found this to be more the case in rodents than humans

Xiao L, Zhang H, Wang Y, Li J, Yang G, Wang L, et al

382 In melanoma models, the probiotic Lactobacillus reuteri produces indole-3-aldehyde, a dietary tryptophan metabolite that enhances local IFN- production by CD8 + T cells, thus increasing antitumor immunity and improving the efficacy of ICIs

Beauchamp MC, Knafo A, Yasmeen A, Carboni JM, Gottardis MM, Pollak MN, et al

Nevertheless, maternal hyperglycemia can deactivate AMPK in the placenta [97]

In addition to these common types of autophagy, there are also selective autophagy forms with specific substrate degradation, including mitochondrial autophagy, lipid droplet autophagy, aggregate autophagy, endoplasmic reticulum autophagy, and ribosomal autophagy (Ma et al., 2024)