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Effects of Kava Components on Inflammation Kavain, dihydrokavain, methysticin, and dihydromethysticin (50 g/mL) were investigated in the context of TNF- production in human acute monocytic leukemia cells, as well as for their response to lipopolysaccharide (LPS)-induced lethality in lab animals [51]

Dig J Nanomater Biostruct 3:3340 Durdureanu-Angheluta A, Pricop L, Stoica I, Peptu CA, Dascalu A, Marangoci N, Doroftei F, Chiriac H, Pinteala M, Simionescu, BC (2010) Synthesis and characterization of magnetite particles covered with -trietoxysilil-polydimethylsiloxane

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Studies on diabetic rats have shown that CGA reduces malondialdehyde (MDA) levels in the kidneys, increases the activity of antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), and decreases the expression of factors involved in oxidative stress and inflammatory responses in the kidney, including IL-6, TNF-, and IL-1 [158]