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Lang F, Busch GL, Ritter M, Volkl H, Waldegger S, Gulbins E, Haussinger D: Functional significance of cell volume regulatory mechanisms

PLoS Pathog 2017

Introduction Oligodendrocytes are glial cells that synthesize myelin, a material that wraps around axons and facilitates neuronal conduction in the central nervous system ( OPCs are highly vulnerable to stress because their metabolic rate and intracellular iron are high, while their concentrations of the antioxidant glutathione are low ( The components of gintonin include lysophosphatidic acids (LPAs), ginseng major latex-like protein 151, and ginseng ribonuclease-like storage protein ( The pathogenesis of the myelin diseases can derive from various stages of oligodendrocyte development, including proliferation, differentiation, and myelination

5 Discussion As a non-apoptotic form of cell death, the underlying mechanism of ferroptosis is complex and intimately connected with other regulatory cell death signaling pathways (Figure 1

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