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310 Importantly, MSCs can also play an immunomodulatory role through direct cellcell contact, whereas MSCs do not always exhibit immunosuppressive effects, which may be determined by local conditions in the microenvironment

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Glucose-6-Phosphate Dehydrogenase Glucose-6-Phosphate Dehydrogenase (G6PDH) catalyzes the rate-limiting step in the oxidative branch of PPP that generates the first molecule of NADPH, therefore its expression and activity are tightly regulated