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106,107,108,109,110,111 Similarly, morphological atrophy and functional asthenia of astrocytes contribute to the pathophysiology of various neurodegenerative diseases such as Alzheimers disease (AD), Parkinsons disease (PD) and Huntingtons disease (HD)

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Astaxanthin has been shown to increase BDNF levels studies in rodents and human cells (in vitro) Improvements in memory are observed in some studies but with variability across demographics These neurocognitive benefits may be through reduced lipid peroxidation Longevity pathways: Astaxanthin mechanistically modulates key longevity genes, including FOXO3, Sirt1, Klotho, and Nrf2

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