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Overall, approximately 50% of detected metabolites exhibited differential levels in control and cKOt kidneys, suggesting that the deletion of Bmal1 has a greater effect on the abundance of metabolites than on their rhythmicity (Figure 3E)

10.1111/jnc.14934 31 CriswellS

However, high dose oral vitamin B12 therapy can also be effective, provided that the dose is sufficient, medication adherence is good, and a response is documented

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Examples of prokaryotic drug resistance genes useful as markers include genes conferring resistance to G418, mycophenolic acid and hygromycin

doi: 10.3390/pharmaceutics13010099 187 ChenBLiFZhuXKXieWHuXZanMHet al