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Sp was able to restore cellular redox homeostasis under induced oxidative stress in mammalian cells and in vivo model, Drosophila where it ameliorated catalase and glutathione peroxidase deficiency

-glutamyl-cysteinyl-glycine) is a small intracellular thiol molecule which is considered as a strong non-enzymatic antioxidant

In most cases, it is not understood whether these diseases are caused by the extra chromosome, the altered metabolic profile, or both

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In addition, nanosheet polyphenolic fractions from propolis demonstrated enhanced antioxidant effects in vitro and in vivo (412)