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CrossRef Wu, J

Discussion Although ALS and FTD are highly heterogenous diseases, the nearly universal convergence on TDP-43 proteinopathy emphasizes a need to understand early drivers of this pathogenic process

Cell 181 (6), 13951405.e11

This interaction supports coordinated regulation of energy metabolism, oxidative homeostasis, and membrane integrity through a division of labor in fatty acid -oxidation, balanced ROS production and scavenging, and membrane lipid synthesis and transport, including ether phospholipids