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Geldanamycin, a new antibiotic

In the 4T1 tumour model, HACS demonstrated superior suppression of both primary tumours and distant metastases compared to the SR-717-unloaded control group, with 90% mouse survival maintained at day 30 (117)

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The human promyelocytic leukemia cell line (HL-60), a model for studying myeloid cell differentiation, can be differentiated into mature neutrophils under a combinational treatment with retinoic acid and G-CSF 38