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Normothermic Machine Perfusion (NMP) might facilitate safe transplantation of marginal organs

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Sickle cell disease: advances in treatment

Self-administration without clinical oversight removes the safety layer that makes the protocol viable

The recycling enzyme anomeric NAM/NAG kinase (AmgK) converts NAM 1 into MurNAc 1-phosphate 1a , which is then converted to UDP-MurNAc 1b by MurNAc -1-phosphate uridylyl transferase (MurU) (Fig