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Characterization of mutational signatures demonstrating adaptive mutability post anti-EGFR therapy in a real-world metastatic colorectal cancer cohort

HIF-1 Semenza and his coworkers [11] discovered HIF-1 in 1992 during a genetic study on erythropoietin (EPO)

GST fusion proteins were purified using GSH-Sepharose resin (Sangon Biotech Co., Ltd., Shanghai, China) and detected using 10% sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE)

However, conflicting findings have also emerged

Selected Publications Groth M, Moissiard G, Wirtz M, Wang H, Garcia-Salinas C, Ramos-Parra PA, Bischof S, Feng S, Cokus SJ, John A, Smith DC, Zhai J, Hale CJ, Long JA, Hell R, D?az de la Garza RI, Jacobsen SE., "MTHFD1 controls DNA methylation in Arabidopsis", Nature Communications (2016)