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Researchers also identified a new class of compounds, "PIPI drugs" (Psychedelic drug Informed but Psychedelic experience Inactive), that retain therapeutic benefits without evoking psychedelic experiences, opening entirely new frontiers for the treatment of mental health and inflammatory disease

PMID: 40813933 SSRN2025 Jan 14

As concerns fibrosis evaluation through cross-sectional imaging techniques, especially magnetic resonance elastography, their use is limited at the moment to tertiary referral centers and for experimental studies, in light of their cost, the limited availability and the procedural length