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Lipid nanoparticles enabling gene therapies: from concepts to clinical utility

Glutathione helps to protect the mitochondria (the cells energy production unit) and the cell membrane

In addition, in cultured VSMCs, chicoric acid impeded PDGF-BB-induced VSMC phenotypic alteration, proliferation, and migration mechanistically by blocking ROS/NF-B/mTOR/P70S6K pathway (83) (Figure 2B)