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During Helicobacter pylori infection in the human gastric mucosa, a specific up-regulation of IDO expression is observed, which regulates multiple helper T-cell lines, resulting in lowered gastric inflammation (Larussa et al., 2015), possibly directly increasing the persistence of the pathogen

However, contrary to this notion, a growing body of evidence supports the health benefits of fish and seafood consumption, indicating that they may not increase, but rather reduce, the risk of IBD

G., Borkham-Kamphorst, E., Tihaa, L., Haas, U

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Until such trials are conducted, a rational approach involving combination therapy is the most appropriate method to treat these patients