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Am J Physiol Endocrinol Metab 304, E853E862

Exposure of human melanocytes to UVB twice and subsequent incubation leads to cellular senescence and senescence-associated pigmentation through the prolonged p53 expression

Annu Rev Genet 40: 409448

Following 90 min of ischemia, clamps were removed and tidal volume restored to 10 mL/kg for 120-min reperfusion

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These conditions are driven by oxidative stress and mitochondrial dysfunction, which lead to the degeneration of retinal cells, including RGCs and photoreceptors [57]