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Another concept is to measure B12 bound to the plasma protein transcobalamin (holoTC, active B12) before and after administration of three high physiological doses of B12 for two days

These are normal signs that your immune system is building protection

Discard at that date, or sooner if the solution turns cloudy, discolors beyond its normal pink-to-red, or shows particulates

Tablets remove many of those variables, which supports cleaner experimental workflows

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