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Immunogenic cell death in cancer and infectious disease

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Mechanistically, loss of the PUFA -oxidation enzyme 2,4-dienoyl-CoA reductase 1 increases cellular PUFA burden, elevates phospholipid hydroperoxides, and triggers ferroptotic death in cancer models 345

This study investigated whether GSH deficiency induces epigenetic alterations that impair Vitamin D (VD) metabolism genes in the livers of HFD-fed mice

Slow expansion of multiple sclerosis iron rim lesions: pathology and 7 T magnetic resonance imaging