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The funding sources of this study had no role in study design, data collection and analysis, decision to publish, or preparation of the article

This was probably because total polyphenol oxidase activity was higher and because laccase can oxidize a wider range of substrates than tyrosinase [5, 7]

The Myers Cocktail is a nutrient cocktail invented by John Myers, a physician from Baltimore, Maryland

For apigenin, nanoformulations such as solid lipid and polymeric nanoparticles have enhanced stability, uptake, and antioxidant effects in metabolic models (88), while ellagic acid phytosome and nano-liposome formulations improved systemic exposure and insulin sensitivity in metabolic dysfunction models (90, 91)

However, in GCLM KO mice, genes encoding lipid synthesis enzymes, Fasn and Scd , were further down-regulated, whereas Fads1 was up-regulated by ethanol, the net effect of which would be expected to result in lower levels of total TG and increases in the relative abundance of certain lipid species