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Cadmium chloride exposure specifically inhibits DNMT3A/3B activity by 70%, impairing de novo methylation processes and contributing to germline instability (89)

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In laboratory settings, Dihexa has been studied for its relationship to cell signaling pathways, receptor interaction, synaptic architecture, and neurobiological communication systems in non-human experimental models

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With these results in hand we became convinced that a clinically useful small molecule analog could be designed that possessed the important characteristics of metabolic stability, extended half-live, BBB penetrability and the capability to enhance cognitive functioning