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We reviewed the current state of research on the clinical application of ICH, highlighting their limitations, and describe the preclinical evidence supporting the use of HPL in the treatment of ICH

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Molecular dynamics in drug design

The interaction occurring between cancer cells and astrocytes can lead to the upregulation of Akt/MAPK, resulting in the overexpression of anti-apoptotic factors including GSTA5, BCL2L1, and TWIST1 in cancer cells to trigger drug resistance [58]