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Co-delivery of doxorubicin and Bcl-2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells

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331(10): 63742 Hodson ME, McKenzie S, Harms HK, et al

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In either case, there is a single extra proton that can readily be transferred between the substrate -amino group and the imine nitrogen of the internal aldimine

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However, off-target effects still cause the risk of normal cell damage and serious side effects

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