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As an immunomodulatory compound, CC-220 can lead a substrate specific ubiquitination of transcription factors Ikaros (IKZF1) and Aiolos (IKZF3) both essential for antibody production (38, 40)

In case of long term treatments, the lower dosages of the product can be employed (600 mg) to be administered by the intramuscular route or slowly by the intravenous route

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See the Fish Oil (Omega-3) Product Review for more details, including the dosage used

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A network pharmacology study identified Sch B, a major metabolite of Fuzheng Huayu formula, as directly binding to PPAR, reducing the viability of HSCs (including T6 and LX-2 cells), and preventing liver fibrosis (123)