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646 Ricoliostat, a selective HDAC6 inhibitor, failed to ameliorate neuropathic pain in patients with DPN when administered 120 mg/kg daily of ricolinostat for 12 weeks compared with placebo

In contrast, the epsilon isoform is severely oncogenic and promotes metastatic squamous cell carcinoma [10]

Although the above preclinical and clinical research results are encouraging, there are still several significant challenges and controversies in developing BBR into a standardized and highly effective anti-diabetic drug

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J., Schaeffer, D