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Gene expression analysis with RTqPCR Gene expression was analyzed via reverse transcriptase quantitative polymerase chain reaction (RTqPCR) using TaqMan probes (Life Technologies) or SSO Universal Probes Master Mix (Bio-Rad)

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Some of the studies involved high doses that came with a hefty dose of side effects

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Clinical Principle If the usual IC/BPS therapies provide no improvement in symptoms, then the clinician should revisit the diagnosis of IC/BPS and consider whether an unidentified disorder may be present that is producing symptoms

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