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Samoylova M, Antonoff MB

About 5-10% of patients require adjusted dosing due to poor response, often from concurrent deficiencies or misdiagnosis

2017 October

LXR regulation of brain cholesterol: from development to disease

Moreover, it has been suggested that starvation reduces liver glycogen storage and hence reduces UGT conjugative ability leading to a greater fraction of the dose being oxidised to NAPQI [77]