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Similarly, NO-based drugs and genes induced a low viability reduction and dependency, also in resistant cell lines (Supplementary Figs

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Colorectal cancer-associated microbiota contributes to oncogenic epigenetic signatures

In the last few years, various GSH modulation-enhanced combinational therapy strategies have been extensively exploited, accompanied by the development of versatile metal-based nanosystems with different structures, functionalities, and treatment performances ( In view of the rapid development of GSH-responsive and -exhausting metal nanomedicines in potentiating cancer therapy, we summarize and outline the recent advancements, mechanisms, prospects, and challenges in this field from different strategies (Scheme 1)