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It was also found that the remaining neurons contain protein inclusions called Lewy bodies (LBs) [4]

Clinical behaviors frequently associated with copper overload autism Sudden emotional outbursts without clear external trigger High irritability or agitation during noise, transitions, or crowds Panic or fear-based behavior Sensory oversensitivity (especially auditory) Hyperactivity alternating with emotional collapse Cyclical mood swings Poor tolerance to stimulants or SSRIs These patterns represent a neurochemical imbalance not behavioral stubbornness or lack of discipline

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This catalytic reaction of GPX4 follows a tert-uni ping pong mechanism, involving redox reactions of the selenocysteine (Ursini and Bindoli, 1987)

Mechanism of malignant hyperthermia (MH) driven by pathogenic RYR1 variants